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Isavuconazole Pharmacodynamic Target Determination for Candida Species in an In Vivo Murine Disseminated Candidiasis Model

Pharmacodynamic (PD) studies with triazoles in the neutropenic murine disseminated candidiasis model have been performed extensively for Candida albicans. They have consistently shown that the pharmacodynamic index most closely correlated with efficacy is the ratio of the 24-h area under the concent...

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Bibliografski detalji
Glavni autori: Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Diekema, Daniel, Andes, David R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811283/
https://ncbi.nlm.nih.gov/pubmed/24002092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01354-13
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