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Isavuconazole Pharmacodynamic Target Determination for Candida Species in an In Vivo Murine Disseminated Candidiasis Model

Pharmacodynamic (PD) studies with triazoles in the neutropenic murine disseminated candidiasis model have been performed extensively for Candida albicans. They have consistently shown that the pharmacodynamic index most closely correlated with efficacy is the ratio of the 24-h area under the concent...

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書誌詳細
主要な著者: Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Diekema, Daniel, Andes, David R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811283/
https://ncbi.nlm.nih.gov/pubmed/24002092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01354-13
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