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In Vivo Pharmacodynamic Target Assessment of Eravacycline against Escherichia coli in a Murine Thigh Infection Model

Eravacycline is a novel fluorocycline antibiotic with potent activity against a broad range of pathogens, including strains with tetracycline and other drug resistance phenotypes. The goal of the studies was to determine which pharmacokinetic/pharmacodynamic (PK/PD) parameter and magnitude best corr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zhao, Miao, Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487610/
https://ncbi.nlm.nih.gov/pubmed/28416552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00250-17
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