載入...

In Vivo Pharmacodynamic Characterization of a Novel Odilorhabdin Antibiotic, NOSO-502, against Escherichia coli and Klebsiella pneumoniae in a Murine Thigh Infection Model

NOSO-502 is a novel odilorhabdin antibiotic with potent activity against Enterobacteriaceae. The goal of these studies was to determine which pharmacokinetic/pharmacodynamic (PK/PD) indices and magnitude best correlated with efficacy in the murine thigh infection model. Six Escherichia coli and 6 Kl...

全面介紹

Na minha lista:
書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Zhao, Miao, Lepak, Alexander J., Marchillo, Karen, VanHecker, Jamie, Andes, David R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125547/
https://ncbi.nlm.nih.gov/pubmed/29987156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01067-18
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!