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In Vivo Pharmacodynamic Target Investigation for Micafungin against Candida albicans and C. glabrata in a Neutropenic Murine Candidiasis Model

Previous studies using in vivo candidiasis models have demonstrated that the concentration-associated pharmacodynamic indices, the maximum concentration of a drug in serum/MIC and 24-h area under the curve (AUC)/MIC, are associated with echinocandin treatment efficacy. The current investigations use...

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Detalhes bibliográficos
Main Authors: Andes, D. R., Diekema, D. J., Pfaller, M. A., Marchillo, K., Bohrmueller, J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565916/
https://ncbi.nlm.nih.gov/pubmed/18625768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00478-08
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