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In Vivo Pharmacodynamics of a New Triazole, Ravuconazole, in a Murine Candidiasis Model
In vivo studies have characterized the pharmacodynamic characteristics of the triazole fluconazole. These investigations demonstrated that the ratio of the area under the concentration-time curve from 0 to 24 h to the MIC (24-h AUC/MIC ratio) is the critical pharmacokinetic/pharmacodynamic (PK/PD) p...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152484/ https://ncbi.nlm.nih.gov/pubmed/12654646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1193-1199.2003 |
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