In Vivo Pharmacodynamics of a New Triazole, Ravuconazole, in a Murine Candidiasis Model

In vivo studies have characterized the pharmacodynamic characteristics of the triazole fluconazole. These investigations demonstrated that the ratio of the area under the concentration-time curve from 0 to 24 h to the MIC (24-h AUC/MIC ratio) is the critical pharmacokinetic/pharmacodynamic (PK/PD) p...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Andes, D., Marchillo, K., Stamstad, T., Conklin, R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1193-1199.2003
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