Non-Natural Peptide Triazole Antagonists of HIV-1 Envelope gp120

We investigated the derivation of non-natural peptide triazole dual receptor site antagonists of HIV-1 Env gp120 in order to establish a path for developing peptidomimetic antiviral agents. Previously, we found that the peptide triazole HNG-156 (R-I-N-N-I-X-W-S-E-A-M-M-CONH(2), where X is ferrocenyl...

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Autori principali: Kamanna, Kantharaju, Aneja, Rachna, Duffy, Caitlin, Kubinski, Pamela, Moreira, Diogo Rodrigo, Bailey, Lauren D, McFadden, Karyn, Schön, Arne, Holmes, Andrew, Tuzer, Ferit, Contarino, Mark, Freire, Ernesto, Chaiken, Irwin M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810028/
https://ncbi.nlm.nih.gov/pubmed/23239505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200422
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