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Sortilin associates with Trk receptors to enhance anterograde transport and signaling by neurotrophins
Binding of target-derived neurotrophins to Trk receptors at nerve terminals are required to stimulate neuronal survival, differentiation, innervation and synaptic plasticity. The distance between the soma and nerve terminal is tremendous, making efficient anterograde Trk transport critical for their...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808973/ https://ncbi.nlm.nih.gov/pubmed/21102451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2689 |
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