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Establishing a cellular FRET-based fluorescence plate reader assay to monitor proNGF-induced cross-linking of sortilin and the neurotrophin receptor p75(NTR)

Whereas the proform of the nerve growth factor (proNGF) is crucial for eliminating superfluous cells during neuronal development it also promotes apoptosis following brain trauma and neuronal injury. The apoptotic signal is elicited upon formation of a trimeric receptor complex also containing the v...

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Detalhes bibliográficos
Publicado no:Int J Biochem Mol Biol
Main Authors: Skeldal, Sune, Kjaergaard, Maj M, Alwasel, Saleh, Nyengaard, Jens R
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700122/
https://ncbi.nlm.nih.gov/pubmed/26823987
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