Establishing a cellular FRET-based fluorescence plate reader assay to monitor proNGF-induced cross-linking of sortilin and the neurotrophin receptor p75(NTR)

Whereas the proform of the nerve growth factor (proNGF) is crucial for eliminating superfluous cells during neuronal development it also promotes apoptosis following brain trauma and neuronal injury. The apoptotic signal is elicited upon formation of a trimeric receptor complex also containing the v...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Biochem Mol Biol
Main Authors: Skeldal, Sune, Kjaergaard, Maj M, Alwasel, Saleh, Nyengaard, Jens R
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700122/
https://ncbi.nlm.nih.gov/pubmed/26823987
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