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PET Imaging of Acetylcholinesterase Inhibitor Induced Effects on α4β2 Nicotinic Acetylcholine Receptor Binding

Acetylcholinesterase inhibitors (AChEIs) are drugs that increase synaptic acetylcholine (ACh) concentrations and are under investigation as treatments for symptoms accompanying Alzheimer’s disease. The goal of this work was to use PET imaging to evaluate alterations of in vivo α4β2 nicotinic acetylc...

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Detalhes bibliográficos
Main Authors: Hillmer, Ansel T, Wooten, Dustin W, Farhoud, Mohammed, Higgins, Andrew T, Lao, Patrick, Barnhart, Todd E, Mukherjee, Jogeshwar, Christian, Bradley T
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806056/
https://ncbi.nlm.nih.gov/pubmed/23913347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21698
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