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The Effects of Lobeline on α4β2* Nicotinic Acetylcholine Receptor Binding and Uptake of [(18)F]Nifene in Rats
Lobeline is a potential smoking cessation drug with affinity for the α4β2 nicotinic acetylcholine receptor and may inhibit the blood-brain barrier (BBB) amine transporter. The goal of this work was to use PET imaging to evaluate the effects of lobeline on the kinetic properties of [(18)F]nifene in t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644313/ https://ncbi.nlm.nih.gov/pubmed/23370310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2013.01.018 |
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