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PET Imaging of α4β2* Nicotinic Acetylcholine Receptors: Quantitative Analysis of [(18)F]Nifene Kinetics in the Nonhuman Primate
[(18)F]Nifene is an α4β2* nicotinic acetylcholine receptor (nAChR) agonist PET radioligand developed to provide accelerated in vivo equilibrium compared to existing α4β2* radioligands. The goal of this work is to analyze the in vivo kinetic properties of [(18)F]nifene with both kinetic modeling and...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580212/ https://ncbi.nlm.nih.gov/pubmed/22851633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.103846 |
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