Human biodistribution and dosimetry of [(18)F]nifene, an α4β2* nicotinic acetylcholine receptor PET tracer

INTRODUCTION: The α4β2* nicotinic acetylcholine receptor (nAChR) system is implicated in many neuropsychiatric pathologies. [(18)F]Nifene is a positron emission tomography (PET) ligand that has shown promise for in vivo imaging of the α4β2* nAChR system in preclinical models and humans. This work es...

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Udgivet i:Nucl Med Biol
Main Authors: Betthauser, Tobey J, Hillmer, Ansel T, Lao, Patrick J, Ehlerding, Emily, Mukherjee, Jogeshwar, Stone, Charles K., Christian, Bradley T
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709231/
https://ncbi.nlm.nih.gov/pubmed/28963927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2017.08.001
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