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Three promoters regulate the transcriptional activity of the human holocarboxylase synthetase gene1,
Holocarboxylase synthetase (HLCS) is the only protein biotin ligase in the human proteome. HLCS-dependent biotinylation of carboxylases plays crucial roles in macronutrient metabolism. HLCS appears to be an essential part of multiprotein complexes in the chromatin that cause gene repression and cont...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805693/ https://ncbi.nlm.nih.gov/pubmed/24075901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2013.06.007 |
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