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The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation
Holocarboxylase synthetase (HCS) catalyzes the binding of biotin to lysines in carboxylases and histones in two steps. First, HCS catalyzes the synthesis of biotinyl-5′-AMP; second, the biotinyl moiety is ligated to lysine residues. It has been proposed that step two is fairly promiscuous, and that...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824026/ https://ncbi.nlm.nih.gov/pubmed/20026029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.017 |
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