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Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism

The role of HLCS in catalyzing of covalent binding of biotin to the 5 human biotin dependent carboxylases is well established, as are the essential roles of these carboxylases in the metabolism of fatty acids, catabolism of leucine, and gluconeogenesis. Here we review recent discoveries regarding th...

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Detalhes bibliográficos
Main Authors: Zempleni, Janos, Liu, Dandan, Camara, Daniel Teixeira, Cordonier, Elizabeth L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043915/
https://ncbi.nlm.nih.gov/pubmed/24684412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nure.12103
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