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Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism

The role of HLCS in catalyzing of covalent binding of biotin to the 5 human biotin dependent carboxylases is well established, as are the essential roles of these carboxylases in the metabolism of fatty acids, catabolism of leucine, and gluconeogenesis. Here we review recent discoveries regarding th...

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Hlavní autoři: Zempleni, Janos, Liu, Dandan, Camara, Daniel Teixeira, Cordonier, Elizabeth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043915/
https://ncbi.nlm.nih.gov/pubmed/24684412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nure.12103
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