Loading...
Effects of single-nucleotide polymorphisms in the human holocarboxylase synthetase gene on enzyme catalysis
Holocarboxylase synthetase (HLCS) is a biotin protein ligase, which has a pivotal role in biotin-dependent metabolic pathways and epigenetic phenomena in humans. Knockdown of HLCS produces phenotypes such as heat susceptibility and decreased life span in Drosophila melanogaster, whereas knockout of...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306849/ https://ncbi.nlm.nih.gov/pubmed/22027809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.198 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|