DROSOPHILA HOLOCARBOXYLASE SYNTHETASE IS A CHROMOSOMAL PROTEIN REQUIRED FOR NORMAL HISTONE BIOTINYLATION, GENE TRANSCRIPTION PATTERNS, LIFESPAN AND HEAT TOLERANCE

Posttranslational modifications of histones play important roles in chromatin structure and genomic stability. Distinct lysine residues in histones are targets for covalent binding of biotin, catalyzed by holocarboxylase synthetase (HCS) and biotinidase (BTD). Histone biotinylation has been implicat...

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Hlavní autoři: Camporeale, Gabriela, Giordano, Ennio, Rendina, Rosaria, Zempleni, Janos, Eissenberg, Joel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626655/
https://ncbi.nlm.nih.gov/pubmed/17056793
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