Nalaganje...
Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62L(LO)FoxP3(+)CD4(+) T cells with limited suppressor activity
IL-2 plays a critical role in the induction and maintenance of FoxP3-expressing regulatory T cells (FoxP3(+)Treg). Reduced expression of IL-2 is linked to T cell-mediated autoimmune diseases such as Type 1 diabetes (T1D), in which an imbalance between FoxP3(+)Treg and pathogenic T effectors exists....
Shranjeno v:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805504/ https://ncbi.nlm.nih.gov/pubmed/21469091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040890 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|