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β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice
IL-35 is a recently identified cytokine exhibiting potent immunosuppressive properties. The therapeutic potential and effects of IL-35 on pathogenic T effector (Teff) cells and Foxp3(+) Treg cells, however, are ill-defined. We tested the capacity of IL-35 to suppress ongoing autoimmunity in NOD mice...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5233468/ https://ncbi.nlm.nih.gov/pubmed/27859048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646493 |
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