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β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice

IL-35 is a recently identified cytokine exhibiting potent immunosuppressive properties. The therapeutic potential and effects of IL-35 on pathogenic T effector (Teff) cells and Foxp3(+) Treg cells, however, are ill-defined. We tested the capacity of IL-35 to suppress ongoing autoimmunity in NOD mice...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Immunol
Egile Nagusiak: Manzoor, Fatima, Johnson, Mark C., Li, Chengwen, Samulski, R. Jude, Wang, Bo, Tisch, Roland
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233468/
https://ncbi.nlm.nih.gov/pubmed/27859048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646493
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