Dolutegravir Pharmacokinetics in the Genital Tract and Colorectum of HIV Negative Men After Single and Multiple Dosing

OBJECTIVES: To describe first dose and steady-state pharmacokinetics (PK) of dolutegravir (DTG) in blood plasma (BP), seminal fluid (SF), colorectal tissue (RT), and rectal mucosal fluid (RF) of healthy HIV negative men. DESIGN: A Phase 1, open label, PK study that enrolled 12 healthy men taking DTG...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Greener, Benjamin N, Patterson, Kristine B, Prince, Heather MA, Sykes, Craig, Adams, Jessica L, Dumond, Julie B, Shaheen, Nicholas J, Madanick, Ryan D, Dellon, Evan S, Cohen, Myron S, Kashuba, Angela DM
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804901/
https://ncbi.nlm.nih.gov/pubmed/23945251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31829ed7a4
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