Differential Penetration of Raltegravir throughout Gastrointestinal Tissue: Implications for Eradication and Cure

OBJECTIVE: To investigate the concentration of the integrase strand inhibitor raltegravir (RAL) throughout gastrointestinal (GI) tissue, especially gutassociated lymphoid tissue (GALT), as an adjunct to current prevention and cure strategies. DESIGN: Open-label pharmacokinetic study METHODS: HIV-neg...

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Main Authors: Patterson, Kristine B., Prince, Heather A., Stevens, Trenton, Shaheen, Nicholas J., Dellon, Evan S., Madanick, Ryan D., Jennings, Steven, Cohen, Myron S., Kashuba, Angela D.M.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016763/
https://ncbi.nlm.nih.gov/pubmed/23945503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835f2b49
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