Virologic and Immunologic Responses to Raltegravir and Dolutegravir in the Gut-Associated Lymphoid Tissue of HIV-Infected Men and Women

BACKGROUND : Raltegravir (RTG) and dolutegravir (DTG) have different pharmacokinetic patterns in the gastrointestinal tract. To determine if this results in pharmacodynamic differences, we compared HIV RNA, HIV DNA, and immunological markers in gut-associated lymphoid tissue (GALT) of HIV-infected p...

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Pubblicato in:Antivir Ther
Autori principali: Weber, Michael D, Andrews, Elizabeth, Prince, Heather A, Sykes, Craig, Rosen, Elias P, Bay, Camden, Shaheen, Nicholas J, Madanick, Ryan D, Dellon, Evan S, Paris, Kristina De, Nelson, Julie AE, Gay, Cynthia L, Kashuba, Angela DM
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376574/
https://ncbi.nlm.nih.gov/pubmed/29714167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP3236
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