The Pharmacokinetics and Viral Activity of Tenofovir in the Male Genital Tract

OBJECTIVE: To measure tenofovir (TFV) concentrations in the male genital tract (GT) after single and multiple doses of tenofovir disoproxil fumarate (TDF) and evaluate the HIV-1 RNA response to monotherapy. DESIGN AND METHODS: A pharmacokinetic study of blood plasma (BP) and GT TFV concentrations in...

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Main Authors: Vourvahis, Manoli, Tappouni, Hiba L., Patterson, Kristine B., Chen, Ya-Chi, Rezk, Naser L., Fiscus, Susan A., Kearney, Brian P., Rooney, James F., Hui, James, Cohen, Myron S., Kashuba, Angela D. M.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726724/
https://ncbi.nlm.nih.gov/pubmed/18197124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181632cc3
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