Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

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Detalhes bibliográficos
Main Authors: Engel, Mark, Sidwell, Tom, Vasanthakumar, Ajithkumar, Grigoriadis, George, Banerjee, Ashish
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3803129/
https://ncbi.nlm.nih.gov/pubmed/24187564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/617595
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