c-Rel Controls Multiple Discrete Steps in the Thymic Development of Foxp3(+) CD4 Regulatory T Cells

The development of natural Foxp3(+) CD4 regulatory T cells (nTregs) proceeds via two steps that involve the initial antigen dependent generation of CD25(+)GITR(hi)Foxp3(−)CD4(+) nTreg precursors followed by the cytokine induction of Foxp3. Using mutant mouse models that lack c-Rel, the critical NF-κ...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Grigoriadis, George, Vasanthakumar, Ajithkumar, Banerjee, Ashish, Grumont, Raelene, Overall, Sarah, Gleeson, Paul, Shannon, Frances, Gerondakis, Steve
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204987/
https://ncbi.nlm.nih.gov/pubmed/22066012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026851
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki