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c-Rel: Shaping CD4 regulatory T cell development in unexpected ways

In the thymus, sequential antigen and cytokine receptor signals direct the stepwise differentiation of multi-potential CD4+CD8+ thymic precursors into Foxp3+ CD4 regulatory T cells (Tregs). In this Point of View article we discuss our recent findings about how the c-Rel transcription factor orchestr...

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Autors principals: Gerondakis, Steve, Fulford, Tom, Grumont, Raelene J.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632621/
https://ncbi.nlm.nih.gov/pubmed/22885978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.21309
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