c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

During thymopoiesis, a unique program of gene expression promotes the development of CD4 regulatory T (T reg) cells. Although Foxp3 maintains a pattern of gene expression necessary for T reg cell function, other transcription factors are emerging as important determinants of T reg cell development....

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Autores principales: Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances, Gerondakis, Steve
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806473/
https://ncbi.nlm.nih.gov/pubmed/19995950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091411
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