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Foxp3(+) regulatory T cells promiscuously accept thymic signals critical for their development
Foxp3(+) regulatory T cells develop in the thymus and are essential for maintaining peripheral tolerance to self tissues. We report the critical requirement for CD154 up-regulation specifically on, and during the thymic development of, Foxp3(+) regulatory T cells for the induction of their clonal ex...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242703/ https://ncbi.nlm.nih.gov/pubmed/18198277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709071105 |
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