Differentiation of regulatory Foxp3(+) T cells in the thymic cortex

Regulatory Foxp3(+) T cells (T(R)) are indispensable for preventing autoimmune pathology in multiple organs and tissues. During thymic differentiation T cell receptor (TCR)–ligand interactions within a certain increased affinity range, in conjunction with γc-containing cytokine receptor signals, ind...

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Bibliografiske detaljer
Main Authors: Liston, Adrian, Nutsch, Katherine M., Farr, Andrew G., Lund, Jennifer M., Rasmussen, Jeffery P., Koni, Pandelakis A., Rudensky, Alexander Y.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575273/
https://ncbi.nlm.nih.gov/pubmed/18695219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801506105
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