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Differentiation of regulatory Foxp3(+) T cells in the thymic cortex
Regulatory Foxp3(+) T cells (T(R)) are indispensable for preventing autoimmune pathology in multiple organs and tissues. During thymic differentiation T cell receptor (TCR)–ligand interactions within a certain increased affinity range, in conjunction with γc-containing cytokine receptor signals, ind...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575273/ https://ncbi.nlm.nih.gov/pubmed/18695219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801506105 |
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