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MicroRNA Targeting Specificity in Mammals: Determinants Beyond Seed Pairing
Mammalian microRNAs (miRNAs) pair to 3'UTRs of mRNAs to direct their posttranscriptional repression. Important for target recognition are ~7-nt sites that match the seed region of the miRNA. However, these seed matches are not always sufficient for repression, indicating that other characterist...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3800283/ https://ncbi.nlm.nih.gov/pubmed/17612493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.017 |
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