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Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

Most metazoan microRNA target sites have perfect pairing to the seed region, located near the miRNA 5’ end. Although pairing to the 3’ region sometimes supplements seed matches or compensates for mismatches, pairing to the central region has been known to function only at rare sites that impart Agro...

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Bibliografiske detaljer
Main Authors: Shin, Chanseok, Nam, Jin-Wu, Farh, Kyle Kai-How, Chiang, H. Rosaria, Shkumatava, Alena, Bartel, David P.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942757/
https://ncbi.nlm.nih.gov/pubmed/20620952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.005
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