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Pairing Beyond the Seed Supports MicroRNA Targeting Specificity
To identify endogenous miRNA target sites, we isolated AGO-bound RNAs from Caenorhabditis elegans by individual-nucleotide resolution crosslinking-immunoprecipitation, which fortuitously also produced miRNA-target chimeric reads. Through the analysis of thousands of reproducible chimeras, pairing to...
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Publicado no: | Mol Cell |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5074850/ https://ncbi.nlm.nih.gov/pubmed/27720646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.09.004 |
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