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Of seeds and supplements: structural insights into extended microRNA–target pairing

Metazoan micro(mi) RNAs guide Argonaute proteins to their targets via perfect pairing to the seed region, located near the 5′ end of the miRNA. In this issue of The EMBO Journal, Sheu‐Gruttadauria et al report the crystal structure of human Argonaute 2 in complex with both a miRNA and target RNA and...

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Dades bibliogràfiques
Publicat a:EMBO J
Autor principal: Fabian, Marc R
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600611/
https://ncbi.nlm.nih.gov/pubmed/31268603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102477
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