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Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice
Osterix (Osx) is essential for both intramembranous or endochondral bone formation. Osteoblast-specific ablation of Osx using Col1α1-Cre resulted in osteopenia, because of impaired osteoblast differentiation in adult mice. Since Osx is also known to be expressed in chondrocytes, we evaluated the rol...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798779/ https://ncbi.nlm.nih.gov/pubmed/23943855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00111.2013 |
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