Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice

Osterix (Osx) is essential for both intramembranous or endochondral bone formation. Osteoblast-specific ablation of Osx using Col1α1-Cre resulted in osteopenia, because of impaired osteoblast differentiation in adult mice. Since Osx is also known to be expressed in chondrocytes, we evaluated the rol...

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Bibliographic Details
Main Authors: Cheng, Shaohong, Xing, Weirong, Zhou, Xin, Mohan, Subburaman
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Molecular Genetics of Complex Traits
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798779/
https://ncbi.nlm.nih.gov/pubmed/23943855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00111.2013
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