Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation

Crohn's disease (CD) is a chronic, immune-mediated, inflammatory disorder of the intestine that has been linked to numerous susceptibility genes, including the immunity-related GTPase (IRG) M (IRGM). IRGs comprise a family of proteins known to confer resistance to intracellular infections throu...

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Detalhes bibliográficos
Main Authors: Liu, Bo, Gulati, Ajay S., Cantillana, Viviana, Henry, Stanley C., Schmidt, Elyse A., Daniell, Xiaoju, Grossniklaus, Emily, Schoenborn, Alexi A., Sartor, R. Balfour, Taylor, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798734/
https://ncbi.nlm.nih.gov/pubmed/23989005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00071.2013
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