Mouse Paneth cell antimicrobial function is independent of Nod2

OBJECTIVE: Although polymorphisms of the NOD2 gene predispose to the development of ileal Crohn's disease, the precise mechanisms of this increased susceptibility remain unclear. Previous work has shown that transcript expression of the Paneth cell (PC) antimicrobial peptides (AMPs) α-defensin...

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Detalhes bibliográficos
Main Authors: Shanahan, Michael T, Carroll, Ian M, Grossniklaus, Emily, White, Andrew, von Furstenberg, Richard J, Barner, Roshonda, Fodor, Anthony A, Henning, Susan J, Sartor, R Balfour, Gulati, Ajay S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844066/
https://ncbi.nlm.nih.gov/pubmed/23512834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304190
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