Mouse Background Strain Profoundly Influences Paneth Cell Function and Intestinal Microbial Composition

BACKGROUND: Increasing evidence supports the central role of Paneth cells in maintaining intestinal host-microbial homeostasis. However, the direct impact of host genotype on Paneth cell function remains unclear. Here, we characterize key differences in Paneth cell function and intestinal microbial...

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Detalhes bibliográficos
Main Authors: Gulati, Ajay S., Shanahan, Michael T., Arthur, Janelle C., Grossniklaus, Emily, von Furstenberg, Richard J., Kreuk, Lieselotte, Henning, Susan J., Jobin, Christian, Sartor, R. Balfour
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288091/
https://ncbi.nlm.nih.gov/pubmed/22384242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032403
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