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Tissue-Specific Transcriptional Regulation has Diverged Significantly between Human and Mouse
We demonstrate that the binding sites for highly conserved transcription factors vary extensively between human and mouse. We mapped the binding of four tissue-specific transcription factors (FOXA2, HNF1A, HNF4A, HNF6) to 4,000 orthologous gene pairs in hepatocytes purified from human and mouse live...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797512/ https://ncbi.nlm.nih.gov/pubmed/17529977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2047 |
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