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Tissue-Specific Transcriptional Regulation has Diverged Significantly between Human and Mouse
We demonstrate that the binding sites for highly conserved transcription factors vary extensively between human and mouse. We mapped the binding of four tissue-specific transcription factors (FOXA2, HNF1A, HNF4A, HNF6) to 4,000 orthologous gene pairs in hepatocytes purified from human and mouse live...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797512/ https://ncbi.nlm.nih.gov/pubmed/17529977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2047 |
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