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A Quantitative Model of Transcriptional Regulation Reveals the Influence of Binding Location on Expression
Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most regulatory proteins bind thousands of sites in mammalian genomes. However, the fu...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861697/ https://ncbi.nlm.nih.gov/pubmed/20442865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000773 |
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