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Unbiased, Genome-Wide In Vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-Specific Liver Gene Expression

We have used a simple and efficient method to identify condition-specific transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-related differences in transcription, which are widespread in mammalian tissues and affect normal physiology, drug response, inflammation, a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ling, Guoyu, Sugathan, Aarathi, Mazor, Tali, Fraenkel, Ernest, Waxman, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976433/
https://ncbi.nlm.nih.gov/pubmed/20876297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00601-10
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