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DNase I Digestion of Isolated Nulcei for Genome-Wide Mapping of DNase Hypersensitivity Sites in Chromatin

DNase I hypersensitivity (DHS) analysis is a powerful method to analyze chromatin structure and identify genomic regulatory elements. Integration of a high throughput detection method into DHS analysis makes genome-wide mapping of DHS sites possible at a reasonable cost. Here we describe methods for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ling, Guoyu, Waxman, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889470/
https://ncbi.nlm.nih.gov/pubmed/23436351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-284-1_3
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