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OTUD5 Regulates p53 Stability by Deubiquitinating p53
BACKGROUND: The p53 tumour suppressor protein is a transcription factor that prevents oncogenic progression by activating the expression of apoptosis and cell-cycle arrest genes in stressed cells. The stability of p53 is tightly regulated by ubiquitin-dependent degradation, driven mainly by its nega...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797110/ https://ncbi.nlm.nih.gov/pubmed/24143256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077682 |
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