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OTUD5 Regulates p53 Stability by Deubiquitinating p53
BACKGROUND: The p53 tumour suppressor protein is a transcription factor that prevents oncogenic progression by activating the expression of apoptosis and cell-cycle arrest genes in stressed cells. The stability of p53 is tightly regulated by ubiquitin-dependent degradation, driven mainly by its nega...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797110/ https://ncbi.nlm.nih.gov/pubmed/24143256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077682 |
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