Targeted Delivery of an Antigenic Peptide to the Endoplasmic Reticulum: Application for Development of a Peptide Therapy for Ankylosing Spondylitis

The development of suitable methods to deliver peptides specifically to the endoplasmic reticulum (ER) can provide some potential therapeutic applications of such peptides. Ankylosing spondylitis (AS) is strongly associated with the expression of human leukocytic antigen-B27 (HLA-B27). HLA-B27 heavy...

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Detalhes bibliográficos
Main Authors: Yu, Hui-Chun, Lu, Ming-Chi, Li, Chin, Huang, Hsien-Lu, Huang, Kuang-Yung, Liu, Su-Qin, Lai, Ning-Sheng, Huang, Hsien-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796468/
https://ncbi.nlm.nih.gov/pubmed/24155957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077451
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