Aberrant expression of interleukin-23-regulated miRNAs in T cells from patients with ankylosing spondylitis

BACKGROUND: Interleukin (IL)-23 can facilitate the differentiation of IL-17-producing helper T cells (Th17). The IL-23/IL-17 axis is known to play a key role in the immunopathogenesis of ankylosing spondylitis (AS). We hypothesized that the expression of microRNAs (miRNAs, miRs) would be regulated b...

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Détails bibliographiques
Publié dans:Arthritis Res Ther
Auteurs principaux: Lai, Ning-Sheng, Yu, Hui-Chun, Tung, Chien-Hsueh, Huang, Kuang-Yung, Huang, Hsien-Bin, Lu, Ming-Chi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247500/
https://ncbi.nlm.nih.gov/pubmed/30463609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1754-1
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