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Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains

Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the spine. AS is highly associated with the expression of HLA-B27. Up to 95% AS patients are HLA-B27-positive. However, only 1%–2% of the HLA-B27-positive carriers suffer from AS, implying that other factors may also g...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Yu, Hui-Chun, Huang, Kuang-Yung, Lu, Ming-Chi, Huang Tseng, Hsien-Yu, Liu, Su-Qin, Lai, Ning-Sheng, Huang, Hsien-Bin
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946993/
https://ncbi.nlm.nih.gov/pubmed/33717069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.591706
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